OCULEX ASIA PHARMACEUTICALS PTE LTD

RMA Projects undertook the project as the constructor providing CSA (Civil, Structural and Architectural) service, M&E (Mechanical and Electrical) services as well as Process Utilities services.  Participation of this project was from the conceptual design phase and included validation activities.

Oculex Asia Pharmaceuticals is a biopharmaceutical manufacturing facility set up to manufacture a series of intra-ocular drugs and is largely a finishing facility with research and development capabilities.  Production spaces are mainly designed as low humidity clean biopharmaceutical clean rooms for the manufacture of powder based products.

• Early participation in the project allows for the implementation of a fully computerized documentation system allowing for all drawings and design documentation to be tracked and updated via computers thus saving time and cost for approvals and documentation.
• Clever manipulation of space and process flow concepts resulting in the optimization of production area and reduced production support areas.  Ratio of space utilization has been reduced from a norm of 1:5 to 1:3.
• Developing a design and construction plan that provides maximum flexibility for the owners to increase and convert production spaces to suit production of future new products.
• Fast track construction management system which not only takes into account procurement issues but also regulatory applications and approvals.  Project was completed in 3 months
• Identifying and increasing the power availability to the facility by 2 times to accommodate the requirements of the owners.

Specific activities accommodated within the facility are as follows;

• Low humidity clean rooms for manufacture of antibiotics and steroids
• Analytical laboratories
• Microbiology laboratory
• Sterility Testing laboratory
• Research and Development laboratories
• Stability rooms
• Technologies for production
• Exploratory and pre-clinical
• Logistics and controls
• Administration